After Jonathan Harker attacks Dracula at his castle (apparently somewhere in Germany), the vampire travels to a nearby city, where he preys on the family of Harker's fiancée. The only one who may be able to protect them is Dr. van Helsing, Harker's friend and fellow-student of vampires, who is determined to destroy Dracula, whatever the cost.
When Jonathan Harker rouses the ire of Count Dracula for accepting a job at the vampire's castle under false pretenses, his friend Dr. Van Helsing pursues the predatory villain.