England, 1897. Abraham Van Helsing receives a letter from his former student Dr John Seward requesting his urgent assistance in the northern town of Whitby, where his fiancée Lucy is showing all the signs of vampirism. Van Helsing follows the bloody trail to the coffin of Count Dracula himself. Van Helsing is a fresh take on the legend of Dracula through the eyes of his greatest enemy.
When his fiancée Lucy falls victim to a mysterious illness, Arthur Holmwood turns to a former rival in her affections - Dr John Seward - for help. Seward calls in his mentor, Professor Van Helsing, who quickly uncovers a terrifying truth.