A lonely Hawaiian girl named Lilo is being raised by her older sister, Nani, after their parents die -- under the watch of social worker Cobra Bubbles. When Lilo adopts a funny-looking dog and names him "Stitch," she doesn't realize her new best friend is a wacky alien created by mad scientist Dr. Jumba.
A young and parentless girl adopts a 'dog' from the local pound, completely unaware that it's supposedly a dangerous scientific experiment that's taken refuge on Earth and is now hiding from its creator and those who see it as a menace.