Red and Liz investigate Orion Relocation Services, an organization that surreptitiously facilitates the disappearance and relocation of criminals. Katarina delves into the memories of an old friend in order to get additional information about the Townsend Directive.
A new FBI profiler, Elizabeth Keen, has her entire life uprooted when a mysterious criminal, Raymond Reddington, who has eluded capture for decades, turns himself in and insists on speaking only to her.