After supervillain Shredder (Brian Tee) escapes custody, he joins forces with mad scientist Baxter Stockman (Tyler Perry) and two dimwitted henchmen, Bebop (Gary Anthony Williams) and Rocksteady (Stephen "Sheamus" Farrelly), to unleash a diabolical plan to take over the world. As the Turtles prepare to take on Shredder and his new crew, they find themselves facing an even greater evil with similar intentions: the notorious Krang.
The Turtles get into another battle with their enemy the Shredder, who has acquired new allies: the mutant thugs Bebop and Rocksteady and the alien being Krang.