FBI trainee Clarice Starling ventures into a maximum-security asylum to pick the diseased brain of Hannibal Lecter, a psychiatrist turned homicidal cannibal. Starling needs clues to help her capture a serial killer. Unfortunately, her Faustian relationship with Lecter soon leads to his escape, and now two deranged killers are on the loose.
A young F.B.I. cadet must receive the help of an incarcerated and manipulative cannibal killer to help catch another serial killer, a madman who skins his victims.