As the war between the vampires and the Lycans rages on, the beautiful vampire, Selene, a former member of the Death Dealers, and Michael, the werewolf hybrid, work together in an effort to unlock the secrets of their respective bloodlines. In this ancient feud between the two tribes, they try to unlock the secrets, in a modern tale of action, intrigue, and forbidden love, which takes them into the battle to end all wars, as the immortals must finally face their doom.—Shewolfinlondon
Picking up directly from the previous movie, vampire warrior Selene and the half werewolf Michael hunt for clues to reveal the history of their races and the war between them.