Mike Milch, an employee of Belko Industries, while driving to work is stopped by street vendors selling "lucky" handmade dolls. Barry Norris, also of Belko Industries, arrives at the remote office building in rural Bogotá, Colombia, to find unfamiliar security guards turning away the local Colombian staff at the gate. New employee Dany Wilkins reports for her first day on the job and is told that a tracking device is implanted in the base of every Belko employee's skull in case they are kidnapped. This is explained as being common in Colombia due to the high incidences of kidnapping.
In a twisted social experiment, eighty Americans are locked in their high-rise corporate office in Bogotá, Colombia, and ordered by an unknown voice coming from the company's intercom system to participate in a deadly game of kill or be killed.