Two years after the events of Scream, Sidney Prescott and Randy are attending Windsor college. They are trying to get on with their lives...Until a new Ghostface killing spree begins. With the help of Dewey and Gale, Sidney must find out who's behind the murders. As the body count goes up, the list of suspects goes down.
Two years after the first series of murders, as Sidney acclimates to college life, someone donning the Ghostface costume begins a new string of killings.